The game begins with the awakening of the player character, a cybernetically-enhanced soldier, from cryosleep to receive a small amount of exposition from a voice identified as a surviving member of the Von Braun's crew, and then immediately has to escape his sick room that has been exposed to space, beginning his long adventure in avoiding his own death. The game involves the maiden voyage of the Von Braun, the first ship with FTL Travel equipped, accompanied by the UNN Rickenbacker.

After UNN (albeit under TriOptimum grant) scientist Marie Delacroix discovers the secret of faster than light travel, UNN and TriOptimum mount a joint mission to Tau Ceti.

The game is set 42 years after the first game due to the events of the first game, anti- Mega-Corp outrage resulted in the formation of the Unified National Nominate, the quasi-socialist world government. It was developed by Looking Glass Studios and Irrational Games, and published by Electronic Arts, releasing on August 11, 1999.

System Shock 2 is a First-Person Shooter/ Immersive Sim with Survival Horror and RPG Elements and the sequel to System Shock.

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